The Modified Wilson Model and Predicting Drug Solubility in Water-Cosolvent Mixtures.
نویسندگان
چکیده
منابع مشابه
Solubility prediction of drugs in water-cosolvent mixtures using Abraham solvation parameters.
PURPOSE To provide predictive cosolvency models, the Abraham solvation parameters of solutes and the solvent coefficients were combined with the Jouyban-Acree and the log-linear models. These models require two and one solubility data points to predict the solubility of drugs in water-cosolvent mixtures. Ab initio prediction methods also were employed and the results were discussed. METHOD Th...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1998
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.46.1058